Sculptra is a polylactic acid biostimulator that initiates controlled and natural deposition of collagen around the site of injection. The collagen deposits gradually and can be maintained for up to 25 months without any further intervention or treatment. The effect of Sculptra is that skin has increased thickness and firmness as it replaces the structural support that is lost during aging.
It is a substance (polymer) that leads to collagen production through a controlled inflammatory response. Response may be influenced by lifestyle habits and individual patient characteristics.
A substance with the ability to generate cellular effect or tissue response.
Sculptra is reconstituted in sterile water. After hydration, Sculptra is injected into the deep dermis (as shown in the illustration) or subcutaneous layer.
The injected volume immediately fills out the wrinkles or corrects volume defects.
Within a few days after injection, the water and other constituents (CMC, mannitol) are absorbed by the body while the Sculptra particles remain in place. The wrinkles or volume defects appear uncorrected again.
Macrophages are recruited and surround the Sculptra particles. Macrophages fuse to giant cells and recruit fibroblasts.
The fibroblasts deposit collagen which provides a structure for the skin. Wrinkles and volume defects are gradually corrected.
Over time the Sculptra particles are degraded, but the collagen deposits remain and provide long-lasting improvement of wrinkles and volume defects.
